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Title: Retrospective analysis of diagnostic accuracy of image guided needle biopsy of pancreatic lesions.
e-poster Number: EPOS 11
Category: e Poster
Author Name: Dr. Swapnil Lamkane
Institute:
Co-Author Name:
Abstract :
AIMS AND OBJECTIVE:
• To determine the diagnostic accuracy of image-guided pancreatic biopsy.
• To determine various factors affecting the yield of pancreatic biopsy.
• To evaluate the diagnostic yield of biopsy and safety of the procedure.
INTRODUCTION:
Pancreatic lesions detected by imaging examinations include cancer, focal pancreatitis, tuberculosis, lymphoma and metastases. However these lesions cannot be easily distinguished by laboratory testing and imaging, so image guided pancreatic biopsy is important to diagnose the lesion.
METHODS:
Patients who underwent image guided pancreatic biopsy from 2015-2021, with availability of post-biopsy histopathological reports were analysed in this study. The total number of patients with post-biopsy HPR reports suggestive of malignancy, benign and infective were calculated and the total numbers of patients whose results came as an insufficient, non-diagnostic, inflammatory, haemorrhagic and non- representative were calculated. PPV, NPV, sensitivity and specificity were also evaluated for the same. Standard used in this study was post operative surgical HPR if patient was operated. In case patient was not operated, follow up imaging to see the imaging/ clinical response of patient after one year of follow up was considered.
RESULTS:
A total of 181 biopsies were studied. Of these, 166 showed diagnostic post biopsy histopathological reports, while 15 were non-diagnostic. These cases were further evaluated with either repeat biopsy, or post-surgical HPR (if operated), or follow up imaging/ clinical response after one year if the patient is not operated. In this retrospective study, we have found high diagnostic accuracy of 91.7%, diagnostic yield 82.87%, sensitivity 90.91 %, specificity 100%, PPV 100% and NPV 51.6 %.
CONCLUSION:
The results of this study were comparable to other similar global studies and shows importance of image guidance in biopsy. High diagnostic accuracy and minimal complication rate has made it an indispensable tool for obtaining histopathological diagnosis and guiding further treatment of patient.
