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Title: UNUSUAL PRESENTATION OF METASTASIS TO THE COLON FROM SQUAMOUS CELL CARCINOMA OF THE CERVIX, A CASE STUDY
e-poster Number: EPOS 12
Category: e Poster
Author Name: Dr. Himanshi Meel
Institute:
Co-Author Name:
Abstract :
Background: - Cervical cancer is the fourth most common cancer among women globally, and the second most common cancer in Indian women. Histologically, about 70% of cervical cancers are squamous cell carcinoma (SCC). The primary routes of metastasis include local invasion and lymphatic spread, with the lungs and para-aortic lymph nodes being the most frequent sites of distant metastasis. Gastrointestinal metastasis from cervical SCC is extremely rare and may be asymptomatic or present with symptoms of intestinal obstruction or bowel perforation.
Case presentation: - A 43-year-old female presented with abdominal pain and discomfort for one week and constipation for 4 days. Past history was significant for a total hysterectomy performed one year prior, with postoperative pathology confirming well-differentiated squamous cell carcinoma of the cervix, for which she received chemoradiotherapy. A PET scan conducted for disease evaluation revealed eccentric mural thickening of sigmoid colon causing lower intestinal obstruction. The colonoscopy showed an ulceroproliferative growth significantly narrowing the sigmoid colon lumen. A biopsy taken from the growth suggested histologic features of metastatic squamous cell carcinoma cervix, confirmed by immunohistochemistry markers.
Conclusion: - Metastatic disease involving the sigmoid colon generally carries a poor prognosis due to its vague symptoms and typically late diagnosis. The treatment strategy for metastatic tumors in the colon originating from cervical SCC remains uncertain. Early detection and timely treatment are essential to prevent severe complications, such as intestinal perforation
